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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca016dd6b6c8fd6683f018ed1f8213e1cbf4024aa8746fd01011eccaa51cae6' 
  AND token = 'I8ZFbHuxgnz6fVeYYg1fZee7/b2qyLrn3Zub3G/8Bmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}