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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5d7b36346f2c015b828248f2f409afa230b6d445d22a4bd3de6941c7064e1e' 
  AND token = 'wS9/47YsbSBYF6E4MAqJJneJC+s/jE6XGhj2tr73H9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}