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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec126351a4a1d545a5d87e5fe3c71a1c245695550836472704f411846c4c2518' 
  AND token = '784q7l+bHKnVXw3XNT+yaJIkwErqwrW35Z6IwQ0VZag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}