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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38f6c6fea4f24436dd99f7ef1ee1c3e50e5d5d2301c463b327fb5880a6a43e5f' 
  AND token = 'NBwQVMXcMEwzDPkDNFUFa44bpaBHkQDpQ2MUsMdCOgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}