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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a736b7d689f7bddc6b1c8f76ac37aac6f4f0cad74b989d9de72fb1cef972daf' 
  AND token = 'p8IO5/U+7RjyXCutfGhG3mSiwnGHBMXmnEPoULDf68Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}