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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca21e771c33a4fb2c6b4024d57c25b2aaf7f0d0f9708ad39e6e9cde485ca138' 
  AND token = 'xNN+A+wiIxEVGihvSuo3L2bYxwOfcao3yevCy8eHE4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}