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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427ab622a9450a6abecdd84bf0e816cc2ea578a18188304b5212395863b8c18e' 
  AND token = 'Yu8KRrUQVs+nleBGLiZ5L5wmx+QGMLthSnqAvq62b1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}