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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecfb4a977684cf0ef3dcafd2b782ff4e5a17c883874a59908752b232201ec7e5' 
  AND token = 'IwOczEs8H7FrpJ+a99IEhHyclYmo+HR6+NCAmcyb9bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}