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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81614f76a324b295025b2202fc5bb887408a689e3a9cc56f0c4d8070aac1fb4e' 
  AND token = 'GcEY6r6yo4MWxzuUOHhJMu1rXR1vZxOSDC3t0Xewslk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}