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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a40788ae9fed46efaa11f0e7c570cf0025af6f6f3e10643fbd6835c17de47a4' 
  AND token = 'ZJ2DMS5nhkDVeM1glbl0Vcu9SYyI0A8FDa4xHLro4Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}