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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd231451e3c3f104a0601ef700b66d778ba93dcb332f04709b6f58c2e23ab2cb3' 
  AND token = 'f6cR2lZBnCgfL3Ayb2D+jx05sSyeSRiNIpW4Y/RmnKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}