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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24cf8a8aefe3319449cc302f34ced4017c6b0aaf5b4ebf5eccc23651cabb3b50' 
  AND token = 'MYtMSDr3msr4BTLe9pE1DyUCgbcXf7KA4Aq/owcAyt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}