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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f810f1124d422a8d0add022c132f6fe3d9aaf1ce4f01c9819ced9705b8b74a9' 
  AND token = 'Q9JXo5hix2xuh3u2ZDMN2BwLmjBsxSo+44vHkKbxZAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}