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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e40d8b0f6dac047b39dc15ceeb81db5e187c99189bd450e207a9248e4820c5aa' 
  AND token = '2F96D69TaRt+Ae+3q5LQZzy/vAuCYVkcQHHFUxbLaYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}