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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5e537eeb19ae9c5fcacfaa77445c725b8a288b8c074cd5c07109b9b4121a912' 
  AND token = 'gbOij6JcaCj3lo/WYxdOUV906by9dRCPy3gTYN/arZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}