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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0101c8a8a9d2b6f1840da505b05e8131f0b0df8d8a3dc4d38c8d951215c3fb04' 
  AND token = '1wP2Zbvgqz2qie0izrjG1EgIaTXCtc/v5+OoZT8GXcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}