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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219efecaf6e250184bcbf3c8b7d1df547f22ed67bc93f639b6235b1fb84e9422' 
  AND token = 'XkFQOl3afcFbbDG9CdDfQwiWtaErrxNBHP/sO33U010=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}