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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c24f7e7df6b57986f12d75ede8351485cee5c72a080fba472d2ce023c4e80f75' 
  AND token = 'IgQlWQv/MfFq+pKp96W5CdIT4vPK5dkFStoUqd+mSWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}