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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48476f47215a909e0855c602a72ec7ca757cc1dcf959f3743dac28253ead311' 
  AND token = 'hL16bkIohSrsObUAPXUFF58ryq/AKpZh6cWBy8wRN8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}