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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b80362566ba452716400c789f413b47964e4be345f0c9743bb61ca14bd4e520' 
  AND token = 'g8LDOH5CbCZzOlJVTidlw5nWD1PNQFsBdUjVPRi9GSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}