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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '532c8eba265ded225755aa511cf5f85e4e2d06ca7c66f317c1bb01bc550b181c' 
  AND token = 'qQpPHxLrd+Ta2GxrajvGcA+ax1Zkz7ArPtK8OzBt1N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}