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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743b94af025300714f5aa4cff0dc3cba265b604e4161c68b027ff989a2d08f61' 
  AND token = 'LzAWm2D5T0VTKAHXV1Wc8sRoOsQwiEvvw+SXwNOfwd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}