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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c6bf58aed254647a468f7376036ce450fbf00e0b9641f65b54030618723d80a' 
  AND token = 'LunaemJE2maKCZHTMcfT7LYl1Pw4wQc0LaoK74SZsUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}