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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66478d7d3d8fc6083218967ff9ec61cb849e5408e1da7b7d7e0b55713eaa1e1' 
  AND token = 'oPjw4Ce7m0SLkfMzFwDE1rVpk9xDjhEpwAQ0bM1wxU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}