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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e571cd5f2d8f90499ff8b2565f6daefd48c5aeed5bbd44e065849530e2dd2f' 
  AND token = 'RcRhwXiLmK8x74Hb4vy7PWYqsJHGkTnoPDUodzPLhAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}