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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5ad5d0e0bcee6488d07f2c98c18fe13d99484d180a781da499ffd5ca51bc0fd' 
  AND token = 'HMathQwXsAutURxh2MWeW8f7GbTx49MEZeXHG3rzMSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}