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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '625ee072ddccd28ce6ce2f49ffb9b019df65a8070dd68e5ae2aa0a5242cae5ba' 
  AND token = 'FqBAcOXVbSGYJ8fQ1ar+LVjg5PHBt5UUck3oismkUtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}