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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1820abd262c0adf521df564f74ec41237a8031f6b98b0088f427e82102e11f' 
  AND token = 'oTi3oDHUqupLvwStIIpUfXEX53PFAHsMYIUqmeTOmHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}