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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427427e843a6138496b347bf0f2786b4d9af50f59b5c1e2cfd63bd47a808f0e1' 
  AND token = '4ujtz6Z2SWUirbc260DQDgQ1sRDojrvSuGYMyxTeB0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}