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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c169165d60565e02492f757549600113ea4b8beb60bbe2e1266c76e8039f5b08' 
  AND token = 'w2ZbD+KvmkNLTC9AIsXbGEDZ8ylG5QideBNq73zQmHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}