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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a8d68079018901f1d396ec5ef039f8968deda22c7feeb0dcbee585b52775503' 
  AND token = 'QIa7L7Yic4vANhWo+bFLUF59fpMwqAU945m9pVB0Gmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}