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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca0ad3c0269cb0918e59be78ac580116c84f61d2979ade70f5e2ecd5b687ca0' 
  AND token = 'jiBh16ObXuXGPmXPJ7f30KhE1yqOfDdGjF1/ZComFiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}