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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3514a9d485bebba3196847bfa5ad48163e9aa8d7dee3ec941b600a71b1999e' 
  AND token = '/vpMAC0Q4bJN/Hp6adoZoKiqPVSqcS2qaJKzv/q4xqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}