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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa6f81104e1c13caaba04ea18a9959651a2d5b248efbf88755e3035795579e63' 
  AND token = 'oIa80EnUExK3YKYZInFWVoxLk1jULEeAZ85qMJAJtEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}