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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b214ac7f4ae346e742b5c823024f54f04b7da7d8dfb07d8d1fee31281848fdd' 
  AND token = 'w/nXUYQK90rh6IXpFL2tsFfbbrLJ7TXQo3zSp+uBDkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}