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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e02c23533da53f72f80a4baac71352f57281321dc4d889f736d1e649910aa1' 
  AND token = 'ykCKRR6zutjalC3dlIr/0pSsLyYR4f5jL2Aq8RSHfGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}