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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746fee221e61785a6d42ce921a178515266c03ed4fcc05366f70525a4c2ec733' 
  AND token = 'E4lnat2vr7LBnGAls8Ns2ZAPQ9fSaafKGCC0J25PMRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}