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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f20507bd711cc0e98eac35b7c1e0e80268949a3ac8ed475fbe8b1ecafe2f2e' 
  AND token = '2cQelCb27OPFqTt3YtEo7LO6eid0w6KMfLI+trmEK1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}