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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be74d925078e6fdaa13593cda78f74e1081b6727e8336c8c9b15d64ff7ae349' 
  AND token = 'AHu3ZF8yvyu1fp4/dHs6/kNZ8MnyIvF9Vmn7VU5Iv94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}