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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '370a96ae80772691f506d5bf09295e4e4ea2aa7a7b5038d838f95be47b087891' 
  AND token = '4iKXEgibEdJw5GkMjr+3/Ql/5SWmL73CfH0rcB1zyVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}