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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c759036a8052c7b4347c91fd7fd7194504814572a71a0476160efb2b50dcbc2f' 
  AND token = 'vOKuyFytLNcUVmSkeTo4KWDr4gBfCe/jIUh5z1xhjnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}