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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a1fc7c51a4a4e52a8d57f971d0570ac74b4fade465ab1a173151b58e8d2763e' 
  AND token = 'CZx5/0Md1X0DKahESrdjgJykgh3Lv0xlvX/oiO3cm2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}