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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60c79d00f051a7553249d0d6dc895923d8807e3641c0c79977c7273631ff9779' 
  AND token = 'RBQqICeEtMJR3RwcwqP/kk/h1dT6GCXQlMBbubZYWBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}