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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cff4f0c00588fc252a243c2746973a9f5350bb10784788019508448f9a5aae67' 
  AND token = 'jmINEyC7ZGfDBGCfFRoDKuuH2D0kdKzf1IIsbVu74wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}