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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c7642098e6107d91c6a2b0c314b3769dafbbe64649d83c5e5b3c38ea1f29cb5' 
  AND token = 'jBMl6KVpzRsWiSBLxNEZ9brXGjMWpRNUjltSaSLf1p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}