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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea98ede8b6c87673ccc610d2ff012e4406b5b472206b5dadb92ad595c3c1a66' 
  AND token = 'CG6SXZXpow12t8UUpdg9JEcWPE1TnqFIkunzsIrhIJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}