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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57549138df4dd92a0929d6a3d5fea41e588d48f581a8e485391ff61f1c2e2019' 
  AND token = 'pdwvpZia6DBSLw8xpnS7o+fPTOpilUwwz3TFEIYVWkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}