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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9e468dc6e94337c88a916e43481b638f1583194aa3ba26671e1d219673365a' 
  AND token = 'URvIfLyxhDvvQroH1LKkJ+gT/c/Rud+oOgSeoDvtjX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}