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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e589eb16cdfb29e695f892a41e1f03d183fac5361a3d96b7b639ec13ce5c33' 
  AND token = 'CRuLREO5jlicpoXp/XN0EvmJIOqA7ymlUcM40Tfim20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}