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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a911e1b8e6b1857eb150b6cf6369cbc564c2a474449c80f7062a66eb359d710b' 
  AND token = 'qg9XoB1NCm8p3WXYnLAfVsqNw6L7Xv6m1ck3IiCi+LI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}